Encodes a protein of unknown function that is involved in cortical microtubule organization. Mutants exhibit abnormal cell growth and patterns of division. TON1A can functionally complement TON1B and their roles appear to be redundant in plants. Encodes a novel protein that is similar to human FOP and OFD1 centrosomal proteins. Localizes to the preprophase band, cytoplasm and cell cortex where it is probably associated with the cortical cytoskeleton. TON1A associates with plant centrins CEN1 and CEN2.
Computational Description
TONNEAU 1A (TON1A); INVOLVED IN: microtubule cytoskeleton organization; LOCATED IN: in 6 components; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: FGFR1 oncogene partner (FOP), N-terminal dimerisation domain (InterPro:IPR018993), LisH dimerisation motif (InterPro:IPR006594); BEST Arabidopsis thaliana protein match is: tonneau 1b (TON1b) (TAIR:AT3G55005.1); Has 229 Blast hits to 226 proteins in 73 species: Archae - 0; Bacteria - 3; Metazoa - 122; Fungi - 0; Plants - 65; Viruses - 0; Other Eukaryotes - 39 (source: NCBI BLink).
